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Fibromyalgia Medication Options

Reducing the head to toe pain of fibromyalgia is the primary goal of most medications your doctor will prescribe. Yet, not every drug works the same way. Some operate in the central nervous system to filter out pain, while other medications target the muscles to ease discomfort. But why should you trust the treatment advice presented below? Isn't it just another ploy to help the drug industry get wealthier? Not at all.

Unlike most websites, the Fibromyalgia Network does not accept any advertisements or grant money from any industry, including Big Pharma. The information below, as well as your other treatment options, is not biased by outside monetary influences. It's based on the published reports in the medical journals and over 22 years of feedback from servicing the fibromyalgia patient community.

Aside from pain-focused treatments, your doctor will likely prescribe a medication to improve your quality of sleep and reduce your daytime fatigue. At this point, other fibromyalgia symptoms of irritable bowel, bladder discomfort, jaw pain, or migraine headaches may seem more tolerable. However, if these or other conditions such as arthritis or peripheral neuropathy persist, your doctor will probably prescribe medication to target your specific regional pains.

Your treatment plan must be individualized according to your symptoms and response to previously prescribed therapies. Which medications are most commonly prescribed for a person with fibromyalgia? In a 2010 Network Medication Survey, patients identified the top 25 drugs prescribed for fibromyalgia. In addition, more than 3,500 patients named nearly 100 different medications to treat their pain, fatigue, and sleep. A brief sampling of possible treatment plans is provided below for common fibromyalgia symptoms.



People with fibromyalgia wake up in the morning feeling unrefreshed because a night in bed does not restore or rejuvenate them.


After pain, fibromyalgia patients rate fatigue as their second worst symptom.9 It is more severe than what people consider as ordinary tiredness and significantly impacts your quality of life. If fatigue is a factor in your fibromyalgia, talk to your doctor. You may be low on thyroid hormone, which is common in 20 to 30 percent of fibromyalgia patients and causes extreme fatigue.10 The good news is that this condition can be determined by a blood test and thyroid hormone can be supplemented. However, if your tests are all normal, your physician may prescribe one of the medications below to help reduce your exhaustion.

What about other treatment options?

If the side effects of medications bowl you over or you wish to limit drug use, read about non-drug therapies and self-help strategies for fibromyalgia.


Are You Getting the Most from Your Medication?

While there are only 3 FDA-approved drugs to treat fibromyalgia, doctors prescribe many different medications to address multiple symptoms.

Find out what both the experts in the field and other patients are saying about meds used to treat fibromyalgia.

Get our Fibro Meds Resource Kit.

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